
France vs Wales Prediction, Odds and Lineups: Best bets for tonight's Six Nations 2025 opener

The Six Nations 2025 explodes into action tonight at the Stade de France where France host Wales, live at 8.15pm on ITV.
France head into this year's tournament as the bookmakers' favourites to lift the Championship Trophy and they will be keen to justify this tag by jetting off to a winning start against a wounded Wales side that lost all five games last time out.
Read on for our prediction, the latest odds, and the starting lineups.
France vs Wales Prediction
France will head into tonight’s clash brimming with confidence after a flawless autumn international campaign, which included a thrilling 30-29 victory over New Zealand.
Meanwhile, Wales are in dismal form, having lost 12 consecutive matches, and they picked up the wooden spoon at last year's Six Nations.
Wales have suffered some bruising defeats during their rough spell, including a 45-24 loss to France and heavy home defeats to South Africa (52-20) and Australia (45-12). With tonight's game set to be a one-sided affair in Paris, bookmakers have priced France as heavy favourites, offering them at odds-on with a big -27.5 handicap.
Given the short odds in the match and handicap markets, my focus shifts to the highly anticipated return of the gold-medal Olympian Antoine Dupont, who is a best-priced 3/1 (BetMGM) to claim the Man of the Match award.
Dupont has been named Player of the Tournament in the last two Six Nations campaigns (2022 Grand Slam & 2023), collecting three Man of the Match awards along the way - making him a strong contender for another individual gong tonight upon his comeback.
France vs Wales Betting Offers
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In what could be a high-scoring affair for France tonight, Paddy Power have boosted winger Louis Bielle-Biarrey from 11/4 to 10/3 to score two or more tries.
The 21-year-old has been in sensational form this season, crossing the line 16 times for Bordeaux Bègles, and he will be eager to make a statement under the lights on Friday night as he heads into the tournament as the 4/1 favourite to finish as the top try-scorer.
Fresh off scoring four tries during the autumn internationals, Bielle-Biarrey’s explosive speed and sharp finishing instincts make him a major threat against a struggling Wales side, who have leaked a combined 97 points in their last two Test matches.
France vs Wales Odds
France, who have beaten Wales in each of the last six meetings, are as short as 1/150 to claim their seventh successive win over their struggling opponents in the opening game of the Six Nations. Meanwhile, Wales are as long as 30/1 to stun the French at the Stade de France, alternatively a draw can be backed at 50/1.
France vs Wales Lineups
France
Starting Lineup: Thomas Ramos, Theo Attissogbe, Pierre-Louis Barassi, Yoram Moefana, Louis Bielle-Biarrey, Romain Ntamack, Antoine Dupont (c), Gregory Alldritt, Paul Boudehent, François Cros, Emmanuel Meafou, Alexandre Roumat, Uini Atonio, Peato Mauvaka, Jean-Baptiste Gros.
Replacements: Julien Marchand, Cyril Baille, Georges-Henri Colombe, Hugo Auradou, Mickael Guillard, Oscar Jegou, Nolann Le Garrec, Emilien Gailleton.
Wales
Starting Lineup: Liam Williams, Tom Rogers, Nick Tompkins, Owen Watkin, Josh Adams, Ben Thomas, Tomos Williams, Aaron Wainwright, Jac Morgan (c), James Botham, Dafydd Jenkins, Will Rowlands, Henry Thomas, Evan Lloyd, Gareth Thomas.
Replacements: Elliot Dee, Nicky Smith, Keiron Assiratti, Freddie Thomas, Tommy Reffell, Rhodri Williams, Dan Edwards, Blair Murray.
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