Lazio vs Bayern Munich Prediction and Betting Tips: Best bets for Wednesday's UCL last-16 encounter

The first phase of Champions League knockout games continue on Wednesday as six-time winners Bayern Munich make the trip to Italy to face Lazio in the pair's last-16 first leg.

Thomas Tuchel's men remain undefeated in this season's competition, dropping points on only one occasion - a home draw with Copenhagen once qualification had already been secured. A 3-0 defeat to Bundesliga table toppers Bayer Leverkusen, who are proving to be a real thorn in their side, puts the retention of their crown in jeopardy, however, an away victory in their first knockout test will do a lot to boost the Germans' confidence again.

The Italians carry a pretty mediocre record heading into this tough clash with the reigning German champions, having won three and lost two in the groups, leaving them 2nd to Atletico Madrid on 10 points in Group E. Domestically, Lazio managed to break a three-game winless run with three points away to Cagliari last Saturday. That being said, their Serie A performance this term sees them sitting five points adrift of the top four having been defeated eight times from 23 matches - the same number as 15th placed Udinese.

Behind Harry Kane, Leroy Sane is Bayern's biggest attacking threat. The forward has made 20 goal contributions in 21 Bundesliga matches, providing a further goal and assist in this competition. Sane struck seven shots on target across the six group stage games, meeting this line in four.

On Lazio's side, Ciro Immobile will lead the line for his side and still holds that cutting edge at 33 years old. He has hit 12 SOT in Serie A, managing 1+ in five of his last six, and a further four in this competition, including one in half of the Group E head-to-heads.

With home advantage, Lazio will want to take a positive result to Germany for the second leg. If they are to do that then Ciro Immobile will be pivotal in this achievement. The club's current and all-time leading scorer has found the back of the net six times in Serie A, as well as picking up six cards in the league too. 

In this specific tournament, he's provided his team with a further three goals and been cautioned once. Having netted in back-to-back games and seeing this bet drop in Lazio's 3-1 win over Cagliari last weekend, we're siding with Immobile to provide consecutive returns in Rome on Wednesday.