Louisville vs. Notre Dame Picks & Best Bets 28th Sep 2024: College Football Week 5 Prediction and Betting Odds

Notre Dame will go up against Louisville in college football action on Saturday at Notre Dame Stadium, starting at 3:30 p.m. ET.

We have run 10,000 simulations of Saturday's CFB matchup using state-of-the-art AI technology to determine the best Louisville vs. Notre Dame bets and predictions.

Our predictions show that Notre Dame will likely win with a projected final score of 25-21.

To get the maximum value from these predictions, we continuously monitor the best odds for each market. This ensures that the sportsbooks listed below are currently offering the highest payouts for the specified plays.

Our Louisville vs. Notre Dame Betting Picks & Predictions

Today's Louisville vs. Notre Dame picks combine the power of AI, stats and analytics to produce NCAAF predictions that are free from the emotional biases often associated with human-made picks.

Louisville vs. Notre Dame Game Information

• Game Date: Saturday, September 28th, 2024
• Game Time: 3:30 p.m. ET
• Location: Notre Dame Stadium
• Spread: Louisville +6.5 / Notre Dame -6.5
• Moneyline: Louisville +200 / Notre Dame -230
• Scoring Total: Over/Under 45 Points (-110/-110)

Louisville +6.5 @ -105 via DraftKings Sportsbook

• According to our simulations, Louisville has a 55% chance of covering the spread, while Notre Dame has a probability of 45%.
• DraftKings Sportsbook offers odds of -105 for Louisville +6.5, presenting a favorable 3.4% edge for them to cover.

Total Points Over 45 @ -110 via DraftKings Sportsbook

• The over/under for total points scored is set at 45 at DraftKings Sportsbook, which offers the best odds for the over at -110.
• Our analysis suggests a 56% likelihood that the total will go over 45 points, providing an edge of 3.3%.

Louisville vs. Notre Dame Moneyline Odds

The sportsbooks have released the moneyline odds for this matchup, with Louisville at +200 via BetMGM, whilst the Notre Dame Notre Dame are available at -230 with FanDuel Sportsbook.

According to the model, Notre Dame is favored to win this game, with our projections assigning them a 64% chance of victory.

Although Notre Dame is more likely to win, BetMGM offers +200 odds on the Louisville moneyline, providing an edge of 2.5%. This makes it our recommended moneyline bet.

Louisville vs. Notre Dame Betting Trends

In addition to our College Football prop picks, we have compiled the best Louisville vs. Notre Dame trends to enhance your research and betting strategy for this game.

Kris Mitchell Over 20.5 Receiving Yards

Kris Mitchell has recorded more than 20.5 receiving yards in 9 of his last 10 games (90% of the time). You can wager on him to record 21+ receiving yards again at odds of -112 (53% implied probability), available at FanDuel.

Jeremiyah Love Over 8.5 Receiving Yards

Jeremiyah Love has had more than 8.5 receiving yards in 4 of his last 5 games (80%). You can place a wager on him to record over 8.5 receiving yards again at odds of -112 (53%), also available at FanDuel.

Tyler Shough Over 225.5 Passing Yards

Tyler Shough has had more than 225.5 passing yards in 6 of his last 8 appearances (75%). You can bet on him to record over 225.5 passing yards again at odds of -112 (53%), again available at FanDuel.

Conclusion

At BettingOdds.com, we are placing a bet on the Louisville +6.5 to cover the spread in this matchup. As for the head-to-head, Notre Dame has a 64% chance of getting the win.

In addition to our Louisville vs. Notre Dame predictions, we offer extensive College Football betting resources. These include the latest College Football odds for today and insightful College Football predictions today to elevate your betting game. Discover top picks with our best College Football bets tonight and dive into our College Football expert insights.