Louisville vs. Clemson Picks & Best Bets 2nd Nov 2024: College Football Week 10 Prediction and Betting Odds

Clemson will go up against Louisville in NCAAF action on Saturday at Memorial Stadium, beginning at 7:30 p.m. ET.
We've performed 10,000 simulations of Saturday's NCAAF matchup using innovative AI technology to determine the best Louisville vs. Clemson bets and predictions.
According to our predictions, Clemson will likely beat Louisville with a projected final score of 36-25.
To get the best value from these predictions, we constantly monitor the most favorable odds for each market. This ensures that the sportsbooks listed below are currently offering the biggest payouts for the plays identified.
Our Louisville vs. Clemson Betting Picks & Predictions
Today's Louisville vs. Clemson picks combine the power of AI, stats and analytics to create college football picks that are free from the emotional biases typical of human-made picks.
Louisville vs. Clemson Game Information
- Game Date: Saturday, November 2nd, 2024
- Game Time: 7:30 p.m. ET
- Location: Memorial Stadium (Clemson, SC)
- Spread: Louisville +11 / Clemson -11
- Moneyline: Louisville +330 / Clemson -400
- Scoring Total: Over/Under 62.5 Points (-105/-110)
Louisville +11 @ -110 via DraftKings Sportsbook
- According to our simulations, Louisville has a 52% chance of covering the spread, while Clemson has a probability of 48%.
- DraftKings Sportsbook offers the best odds for this bet at -110.
Total Points Under 62.5 @ -110 via DraftKings Sportsbook
- The over/under for total points scored is set at 62.5, with DraftKings Sportsbook offering the best odds for the under at -110.
- Our analysis shows a 51% chance that the total will stay under 62.5 points.
Louisville vs. Clemson Moneyline Odds
The sportsbooks have released the moneyline odds for this matchup, with Louisville at +330 via FanDuel Sportsbook, whilst the Clemson Clemson are available at -400 with BetMGM.
According to the model, Clemson is favored to win this game, with our projections giving them a 72% chance of prevailing.
Although Clemson is more likely to win, FanDuel Sportsbook offers +330 odds on the Louisville moneyline, providing an edge of 4.7%. This makes it our recommended moneyline bet.
Louisville vs. Clemson Betting Trends
In addition to our College Football prop picks, we have sourced the best Louisville vs. Clemson trends to enhance your research and betting strategy for this game.
Ja'Corey Brooks Over 80.5 Receiving Yards
Ja'Corey Brooks has recorded more than 80.5 receiving yards in 7 of his last 8 games (88% of the time). You can put money on him to go over 80.5 receiving yards again at odds of -112 (53% implied probability), available at FanDuel.
Cade Klubnik Over 2.5 Passing Touchdowns
Cade Klubnik has had more than 2.5 passing touchdowns in 5 of his last 6 games (83%). You can place a bet on him to record over 2.5 passing touchdowns again at odds of +100 (50%), available at Bet365.
Tyler Shough Over 257.5 Passing Yards
Tyler Shough has had more than 257.5 passing yards in 6 of his last 7 appearances (86%). You can wager on him to record over 257.5 passing yards again at odds of -112 (53%), again available at FanDuel.
Conclusion
At BettingOdds.com, we're betting on the Louisville +11 to cover the spread in this matchup. As for the head-to-head, Clemson has a 72% chance of getting the win.
Beyond our Louisville vs. Clemson predictions, we offer a wide range of College Football betting resources. These include the latest College Football odds for today and insightful College Football predictions for today to elevate your betting game. Discover top picks with the College Football best bets today and dive into Kyle Odegard's College Football insights.