Titans vs. Colts Picks & Best Bets 22nd Dec 2024: NFL Week 16 Prediction, Betting Odds, Player Props & Trends

The Indianapolis Colts will host the Tennessee Titans in NFL action on Sunday at Lucas Oil Stadium, starting at 1:00 p.m. ET.
We run 10,000 simulations of Sunday's NFL matchup using innovative AI technology to pinpoint the best Titans vs. Colts bets, player props and predictions.
According to our predictions, the Colts will likely defeat the Titans with a projected final score of 23-19.
To get the maximum value from these predictions, we continually monitor the best odds for each market. This ensures that the sportsbooks listed below are currently offering the biggest payouts for the specified plays.
Our Titans vs. Colts Betting Picks & Predictions
Today's Titans vs. Colts picks combine the power of AI, statistics and analytics to produce NFL picks that are free from the emotional biases often associated with human-made picks.
Titans vs. Colts Game Information
- Game Date: Sunday, December 22nd, 2024
- Game Time: 1:00 p.m. ET
- Location: Lucas Oil Stadium
- Spread: Titans +4 / Colts -4
- Moneyline: Titans +172 / Colts -190
- Scoring Total: Over/Under 42.5 Points (-110/-105)
Titans +4 @ -108 via DraftKings Sportsbook
- According to our simulations, the Titans have a 52% chance of covering the spread, while the Colts have a probability of 48%.
- DraftKings Sportsbook offers the best odds for this bet at -108.
Total Points Over 42.5 @ -110 via BetMGM
- The over/under for total points scored is set at 42.5 at BetMGM, which offers the best odds for the over at -110.
- Our analysis suggests a 51% chance that the total will go over 42.5 points.
Titans vs. Colts Moneyline Odds
The sportsbooks have released the moneyline odds for this matchup, with the Tennessee Titans at +172 via FanDuel Sportsbook, whilst the Indianapolis Colts are available at -190 with BetMGM.
According to the model, the Colts are favored to win this game, with our projections assigning them a 63% chance of prevailing.
Even though the Colts are more likely to win, FanDuel Sportsbook offers +172 odds on the Titans moneyline, providing an edge of 0%. This makes it our recommended moneyline bet.
Our Player Prop Picks for Titans vs. Colts
Here, we have outlined the projected player stats for the top offensive players on each team. We have then compared these projections to the odds and lines with the sportsbooks to produce NFL player props for Sunday's Titans vs. Colts game.
Tennessee Titans Prediction
Player | Proj. Rush Yds | TD Prob. |
---|---|---|
Tony Pollard | 54 yds | 42% |
Tyjae Spears | 29 yds | 32% |
Mason Rudolph | 10 yds | 13% |
Player | Proj. Rec Yds | TD Prob. |
---|---|---|
Calvin Ridley | 51 yds | 37% |
Nick Westbrook-Ikhine | 37 yds | 30% |
Chigoziem Okonkwo | 23 yds | 19% |
Tyler Boyd Under 2.5 Receptions (-150)
Pick | Operator | New Users | Odds |
---|---|---|---|
Tyler Boyd Under 2.5 Receptions | DraftKings Sportsbook | Get Offer | -150 |
- Our top prop bet for the Titans is for Tyler Boyd to record under 2.5 receptions.
- Our analysis projects this prop to have a probability of 88.1%, giving us an edge of 28.1% on the -150 odds offered by DraftKings.
Indianapolis Colts Prediction
Player | Proj. Rush Yds | TD Prob. |
---|---|---|
Jonathan Taylor | 75 yds | 54% |
Anthony Richardson | 39 yds | 47% |
Trey Sermon | 8 yds | 4% |
Player | Proj. Rec Yds | TD Prob. |
---|---|---|
Michael Pittman | 60 yds | 28% |
Josh Downs | 54 yds | 32% |
Adonai Mitchell | 37 yds | 21% |
Adonai Mitchell Over 1.5 Receptions (-170)
Pick | Operator | New Users | Odds |
---|---|---|---|
Adonai Mitchell Over 1.5 Receptions | DraftKings Sportsbook | Get Offer | -170 |
- Our best prop bet for the Colts is for Adonai Mitchell to record over 1.5 receptions.
- According to our analysis, this prop has a probability of 89.7%, providing an edge of 26.8% on the -170 odds offered by DraftKings.
These NFL player props today are based purely on advanced modeling techniques that factor in variables including but not limited to past form and opponent trends, meaning you can trust that there is no bias that comes into play.
Titans vs. Colts Betting Trends
In addition to our NFL prop picks, we have compiled the best Titans vs. Colts trends to enhance your research and betting strategy for this matchup.
Anthony Richardson Over 44.5 Rushing Yards
Anthony Richardson has recorded more than 44.5 rushing yards in 5 of his last 6 appearances (83% of the time). You can put money on him to go over 44.5 rushing yards again at odds of -110 (52% implied probability), available at FanDuel.
Mason Rudolph Over 10.5 Rushing Yards
Mason Rudolph has had more than 10.5 rushing yards in 5 of his last 6 appearances (83%). You can place a wager on him to record over 10.5 rushing yards again at odds of -110 (52%), available at Bet365.
Jonathan Taylor Over 20.5 Rushing Attempts
Jonathan Taylor has had more than 20.5 rushing attempts in 4 of his last 5 appearances (80%). You can wager on him to record over 20.5 rushing attempts again at odds of +100 (50%), again available at FanDuel.
Conclusion
At BettingOdds.com, we're backing Tyler Boyd of the Titans to record Receptions 2.5 receptions, with an edge of 28.1% marking this as our top prop bet of the game. Additionally, we're placing a bet on the Titans +4 to cover.
Beyond our Titans vs. Colts predictions, we offer extensive NFL betting tools. These include the latest NFL odds and insightful NFL computer picks to elevate your betting game. Discover top picks with our best NFL bets and dive into Kyle Odegard's NFL insights. Plus, find the best odds and promotions with our guide to the best online NFL betting sites.