Lions vs. 49ers Picks & Best Bets 30th Dec 2024: NFL Week 17 Prediction, Betting Odds, Player Props & Trends

The San Francisco 49ers will face the Detroit Lions in NFL action on Monday at Levi's Stadium, starting at 8:15 p.m. ET.
We performed 10,000 simulations of Monday's NFL matchup using innovative AI technology to determine the best Lions vs. 49ers bets, player props and predictions.
According to our predictions, the Lions will likely win with a projected final score of 26-22.
To get the best value from these predictions, we constantly monitor the best odds for each market. This means that the sportsbooks listed below are currently offering the highest payouts for the plays identified.
Our Lions vs. 49ers Betting Picks & Predictions
Today's Lions vs. 49ers picks fuse the power of AI, stats and analytics to create NFL predictions that are free from the emotional biases typical of human-made picks.
Lions vs. 49ers Game Information
- Game Date: Monday, December 30th, 2024
- Game Time: 8:15 p.m. ET
- Location: Levi's Stadium
- Spread: Lions -3.5 / 49ers +3.5
- Moneyline: Lions -205 / 49ers +200
- Scoring Total: Over/Under 50.5 Points (-108/-110)
Lions -3.5 @ -110 via FanDuel Sportsbook
- According to our simulations, the Lions have a 52% chance of covering the spread, while the 49ers have a probability of 48%.
- FanDuel Sportsbook offers the best odds for this bet at -110.
Total Points Under 50.5 @ -110 via DraftKings Sportsbook
- The over/under for total points scored is set at 50.5 at DraftKings Sportsbook, which offers the best odds for the under at -110.
- Our analysis suggests a 53% likelihood that the total will stay under 50.5 points, providing an edge of 0.6%.
Lions vs. 49ers Moneyline Odds
The sportsbooks have released the moneyline odds for this matchup, with the Detroit Lions at -205 via FanDuel Sportsbook, whilst the San Francisco 49ers are available at +200 with BetMGM.
According to the model, the Lions are favored to win this game, with our projections giving them a 63% chance of prevailing.
Although the Lions are more likely to win, BetMGM offers +200 odds on the 49ers moneyline, providing an edge of 3.7%. This makes it our recommended moneyline bet.
Our Player Prop Picks for Lions vs. 49ers
Here, we have outlined the projected player stats for the top offensive players on each team. We have then compared these projections to the odds and lines with the sportsbooks to produce NFL player props for Monday's Lions vs. 49ers matchup.
Detroit Lions Prediction
Player | Proj. Rush Yds | TD Prob. |
---|---|---|
Jahmyr Gibbs | 102 yds | 67% |
Craig Reynolds | 19 yds | 14% |
Jermar Jefferson | 15 yds | 3% |
Player | Proj. Rec Yds | TD Prob. |
---|---|---|
Amon-Ra St. Brown | 79 yds | 47% |
Jameson Williams | 52 yds | 39% |
Sam LaPorta | 49 yds | 32% |
Jahmyr Gibbs Over 83.5 Rushing Yards (-110)
Pick | Operator | New Users | Odds |
---|---|---|---|
Jahmyr Gibbs Over 83.5 Rushing Yards | FanDuel Sportsbook | Get Offer | -110 |
- Our top prop bet for the Lions is for Jahmyr Gibbs to record over 83.5 rushing yards.
- Our analysis projects this prop to have a probability of 67.2%, giving us an edge of 14.8% on the -110 odds offered by FanDuel.
San Francisco 49ers Prediction
Player | Proj. Rush Yds | TD Prob. |
---|---|---|
Isaac Guerendo | 73 yds | 42% |
Deebo Samuel | 12 yds | 45% |
Brock Purdy | 11 yds | 18% |
Player | Proj. Rec Yds | TD Prob. |
---|---|---|
George Kittle | 63 yds | 41% |
Jauan Jennings | 59 yds | 37% |
Deebo Samuel | 54 yds | 45% |
Brock Purdy Under 22.5 Rushing Yards (-125)
Pick | Operator | New Users | Odds |
---|---|---|---|
Brock Purdy Under 22.5 Rushing Yards | DraftKings Sportsbook | Get Offer | -125 |
- Our best prop bet for the 49ers is for Brock Purdy to record under 22.5 rushing yards.
- According to our analysis, this prop has a probability of 84.4%, giving us an edge of 28.8% on the -125 odds offered by DraftKings.
These NFL player props today are based purely on advanced modeling techniques that factor in variables including but not limited to past form and opponent trends, meaning you can trust that there is no bias that comes into play.
Lions vs. 49ers Betting Trends
In addition to our NFL prop picks, we have compiled the best Lions vs. 49ers trends to enhance your research and betting strategy for this matchup.
Jared Goff Over 31.5 Passing Attempts
Jared Goff has recorded more than 31.5 passing attempts in 5 of his last 5 games (100% of the time). You can wager on him to go over 31.5 passing attempts again at odds of -135 (57% implied probability), available at DraftKings.
Jared Goff Over 247.5 Passing Yards
Jared Goff has had more than 247.5 passing yards in 5 of his last 6 appearances (83%). You can place a wager on him to record over 247.5 passing yards again at odds of -110 (52%), available at Bet365.
Jared Goff Over 1.5 Passing Touchdowns
Jared Goff has had more than 1.5 passing touchdowns in 6 of his last 7 appearances (86%). You can wager on him to record over 1.5 passing touchdowns again at odds of -130 (57%), available at FanDuel.
Conclusion
At BettingOdds.com, we're backing Brock Purdy of the 49ers to record Rushing Yards 22.5 rushing yards, with an edge of 28.8% marking this as our top prop bet of the game. Additionally, we're placing a bet on the Lions -3.5 to cover.
Beyond our Lions vs. 49ers predictions, we offer a wide range of NFL betting tools. These include the latest NFL odds and insightful NFL predictions for today to elevate your betting game. Discover top picks with the NFL best bets today and dive into Kyle Odegard's NFL insights. Plus, find the best odds and promotions with our guide to the best NFL betting sites.