NFL Parlay Picks Today: Thanksgiving Day Parlay Bet @ +385 odds 11/23

Happy Turkey Day. It’s time to eat, watch football and make some NFL picks in between conversation with the in-laws. It’s a big day for the NFL with three games going back-to-back.

The best way to build the excitement? A daily parlay involving every one of the matchups. I picked two spreads and one moneyline for a potential payout at +385 odds.

Here are the three NFL picks I am combining, with the rationale below.

Spread: Green Bay Packers +7.5 (-110); Dallas Cowboys -11 (-110)
Moneyline: San Francisco 49ers ML (-300)
Parlay odds: +385 at BetMGM

Leg 1: Green Bay Packers +7.5 at Detroit Lions

• The Packers are giving up just 17.6 points per game since a 34-20 loss to the Lions in Week 4 
• Packers QB Jordan Love was poor in the first meeting and has finished top-10 in Total QBR each of the past two weeks
• Green Bay has only lost two games this season by more than seven points

Leg 2: Dallas Cowboys -11 vs. Washington Commanders

• The Cowboys are No. 3 in defensive efficiency and boast one of the best pass-rushes in the NFL
• Commanders QB Sam Howell has been sacked an NFL-high 51 times in 11 games this year
• Cowboys QB Dak Prescott is No. 2 in Total QBR and the Commanders are now without recently-traded d-linemen Montez Sweat and Chase Young

Leg 3: San Francisco 49ers moneyline at Seahawks

• The 49ers are No. 2 in Team DVOA and have a point-differential of plus-122, second-best in the NFL
• Seahawks QB Geno Smith was No. 7 in Total QBR last season but is down to No. 17 this year
• Seattle is a quality team playing at home so choosing the moneyline gives wiggle room with the spread