MLB Best Bets & Expert Picks for Today 27th September 2024

Get ready for baseball on Friday, September 27, with 12 regular-season MLB games to bet on today.

Our predictive analytics model has simulated the outcome of each matchup on today's slate and identified the top five betting opportunities, with the best bet of the day coming in the Padres vs. Diamondbacks matchup at 9:40PM ET.

We're also placing wagers on the Astros vs. Guardians and Reds vs. Cubs, ensuring an exciting Friday for MLB betting.

MLB Best Bets for Today

Friday's MLB slate features five bets with a betting edge according to our model. The best value is over 8.5 runs in the Padres-Diamondbacks game, offering an edge of 9.3% at odds of -112.

Top MLB Picks for 27th September 2024

Prepare for an exciting day of baseball action with our top picks for 27th September 2024. These picks provide valuable opportunities for success, thanks to detailed data analysis and predictive algorithms.

Having analyzed every run line, total and moneyline, each pick is methodically chosen to deliver an edge in today's baseball matchups.

Amplify your Friday betting experience with these expertly curated predictions that are free from the emotional biases typical of human-made picks.

Padres vs. Diamondbacks Over 8.5 Runs (-112)

• Padres vs. Diamondbacks (9:40PM ET, Friday)
• 9.3% edge
• 62.1% probability
• Best odds available with FanDuel Sportsbook

With a calculated edge of 9.3% and a significant probability of 62.1%, the over 8.5 runs bet at -112 is our best bet for today's baseball. Don't miss this top bet in the Padres vs. Diamondbacks matchup at 9:40PM ET, available at FanDuel Sportsbook.

Astros vs. Guardians Over 8 Runs (-102)

• Astros vs. Guardians (7:10PM ET, Friday)
• 9.3% edge
• 59.8% probability
• Best odds available with DraftKings Sportsbook

With a probability of 59.8% and an edge of 9.3%, the over 8 runs bet at -102 is another strong play. Place your bet on this +EV pick in the Astros vs. Guardians game before it begins at 7:10PM ET, with the best odds available at DraftKings Sportsbook.

Reds vs. Cubs Over 6.5 Runs (-110)

• Reds vs. Cubs (2:20PM ET, Friday)
• 8.6% edge
• 61% probability
• Best odds available with BetMGM

Featuring an edge of 8.6% and a solid probability of 61%, the over 6.5 runs bet at -110 with BetMGM is our next recommended wager for Friday. Don't let these odds pass by in the Reds vs. Cubs matchup at 2:20PM ET.

Marlins vs. Blue Jays Over 8 Runs (-115)

• Marlins vs. Blue Jays (7:07PM ET, Friday)
• 8.2% edge
• 61.7% probability
• Best odds available with BetMGM

Today's next pick is over 8 runs at -115, with a significant probability of 61.7% and an edge of 8.2%. Don't miss out on this prime betting chance in the Marlins vs. Blue Jays matchup at 7:07PM ET, available at BetMGM.

Orioles vs. Twins Over 8 Runs (-112)

• Orioles vs. Twins (8:10PM ET, Friday)
• 8.1% edge
• 60.9% probability
• Best odds available with DraftKings Sportsbook

Our MLB analysis highlights the over 8 runs at -112 as another +EV bet, backed by an edge of 8.1% and a strong 60.9% likelihood of coming through. Jump on this advantageous wager in the Orioles vs. Twins game at 8:10PM ET, available at DraftKings Sportsbook.

Best MLB Parlay for Friday

Friday's MLB parlay consists of three legs, offering odds of +457 at FanDuel Sportsbook.

Conclusion

At BettingOdds.com, our MLB play of the day is over 8.5 runs in the Padres vs. Diamondbacks game. Additionally, we have four further bets and a +457 parlay, offering value for those seeking data-driven action on today's baseball slate.

In addition to our Friday MLB best bets and parlay, we offer extensive MLB betting tools. These include the latest MLB odds tonight and insightful MLB predictions today to elevate your betting game. Discover top picks with our best MLB bets and dive into our MLB expert insights. Plus, find the best odds and promotions with our guide to the top online MLB betting sites.