MLB Best Bets & Expert Picks for Today 21st September 2024

It's time for baseball on Saturday, September 21, featuring 15 regular-season MLB games that we can bet on today.

Our predictive analytics model has simulated the outcome of each game on today's slate and identified the top five betting opportunities, with the best bet of the day coming in the Twins vs. Red Sox matchup at 4:10PM ET.

We're also placing wagers on the Pirates vs. Reds and Guardians vs. Cardinals, making this an exciting Saturday for MLB betting.

MLB Best Bets for Today

Saturday's MLB action features five bets with an edge according to our model. The best value is over 7.5 runs in the Twins-Red Sox game, offering an edge of 7.9% at odds of -115.

Top MLB Picks for 21st September 2024

Prepare for a riveting day of baseball action with our top picks for 21st September 2024. These plays offer valuable opportunities for success, based on carefully constructed data analysis and predictive algorithms.

Having analyzed every run line, total and moneyline, each pick is methodically chosen to provide an edge in today's baseball matchups.

Amplify your Saturday betting session with these strategically curated predictions that are free from the emotional biases often associated with human-made picks.

Twins vs. Red Sox Over 7.5 Runs (-115)

• Twins vs. Red Sox (4:10PM ET, Saturday)
• 7.9% edge
• 61.4% probability
• Best odds available with DraftKings Sportsbook

With a calculated edge of 7.9% and a strong probability of 61.4%, the over 7.5 runs bet at -115 is our top pick for today's baseball. Don't miss this top bet in the Twins vs. Red Sox matchup at 4:10PM ET, available at DraftKings Sportsbook.

Pirates -1.5 (+155)

• Pirates vs. Reds (1:10PM ET, Saturday)
• 6.1% edge
• 45.3% probability
• Best odds available with FanDuel Sportsbook

With a probability of 45.3% and an edge of 6.1%, the Pirates -1.5 run line bet at +155 is another valuable option. Place your bet on this high-value pick in the Pirates vs. Reds game before it begins at 1:10PM ET, with the best odds available at FanDuel Sportsbook.

Red Sox ML (+128)

• Twins vs. Red Sox (4:10PM ET, Saturday)
• 5.2% edge
• 49.1% probability
• Best odds available with FanDuel Sportsbook

Featuring an edge of 5.2% and a probability of 49.1%, the Red Sox ML bet at +128 with FanDuel Sportsbook is our next top bet for Saturday. Don't let this chance pass by in the Twins vs. Red Sox matchup at 4:10PM ET.

Guardians vs. Cardinals Over 7.5 Runs (-115)

• Guardians vs. Cardinals (7:15PM ET, Saturday)
• 4.8% edge
• 58.3% probability
• Best odds available with DraftKings Sportsbook

Today's fourth pick is over 7.5 runs at -115, with a probability of 58.3% and an edge of 4.8%. Take advantage of this top betting opportunity in the Guardians vs. Cardinals matchup at 7:15PM ET, available at DraftKings Sportsbook.

Angels vs. Astros Over 7.5 Runs (-115)

• Angels vs. Astros (7:10PM ET, Saturday)
• 4.7% edge
• 58.2% probability
• Best odds available with DraftKings Sportsbook

Our MLB analysis shows the over 7.5 runs at -115 as another +EV wager, backed by an edge of 4.7% and a 58.2% probability of coming through. Jump on this favorable bet in the Angels vs. Astros game at 7:10PM ET, available at DraftKings Sportsbook.

Best MLB Parlay for Saturday

Saturday's MLB parlay consists of three legs, offering odds of +553 at DraftKings Sportsbook.

Conclusion

At BettingOdds.com, our MLB play of the day is over 7.5 runs in the Twins vs. Red Sox game. Additionally, we have four further bets and a +553 parlay, offering value for those seeking data-driven action on today's baseball slate.

In addition to our Saturday MLB best bets and parlay, we offer extensive MLB betting tools. These include the latest MLB odds and insightful MLB computer picks to elevate your betting game. Discover top picks with our MLB best bets today and dive into our MLB insights. Plus, find the best odds and promotions with our guide to the top MLB betting sites.